| Transactions |
| Date | Team | Player | Type | OthTm | EffDate | When |
| 4/12/1922 | Alt | Goodwin | Demoted to reserve roster | | | Before |
| 4/12/1922 | Alt | Russell,J | Demoted to reserve roster | | | Before |
| 4/12/1922 | Alt | Vick | Demoted to reserve roster | | | Before |
| 5/17/1922 | Mac | Ellerbe | Acquired via trade | Tex | | After |
| 5/17/1922 | Mac | Ogden | Traded away | Tex | | After |
| 5/17/1922 | Tex | Ellerbe | Traded away | Mac | | After |
| 5/17/1922 | Tex | Ogden | Acquired via trade | Mac | | After |
| 5/29/1922 | Mid | Ward,C | Traded away | Tex | | After |
| 5/29/1922 | Tex | Ward,C | Acquired via trade | Mid | | After |
| 5/30/1922 | Tex | Blankenship,H | Demoted to reserve roster | | | Before |
| 5/30/1922 | Tex | McGrew | Released | | | Before |
| 6/11/1922 | Tex | Maguire | Promoted to active roster | | | Before |
| 6/11/1922 | Tex | McCabe | Demoted to reserve roster | | | Before |
| 6/16/1922 | Mid | Cruise | Acquired via trade | BB | | After |
| 6/16/1922 | Mid | Veach | Traded away | BB | | After |
| 7/1/1922 | Alt | Duncan | Traded away | DBL | | After |
| 7/1/1922 | Alt | Leverett | Traded away | DBL | | After |
| 7/1/1922 | Alt | Pfeffer | Traded away | DBL | | After |
| 7/1/1922 | Alt | Stock | Traded away | DBL | | After |
| 7/1/1922 | Bla | Collins,P | Traded away | DBL | | After |
| 7/1/1922 | Bla | Ruth | Traded away | DBL | | After |
| 7/1/1922 | KS | Decatur | Traded away | DBL | | After |
| 7/1/1922 | KS | Faber | Traded away | DBL | | After |
| 7/1/1922 | KS | Witt | Traded away | DBL | | After |
| 7/1/1922 | Mac | Meusel,I | Traded away | DBL | | After |
| 7/1/1922 | Mac | Sisler | Traded away | DBL | | After |
| 7/1/1922 | Mid | Lee | Traded away | DBL | | After |
| 7/1/1922 | Mid | McManus | Traded away | DBL | | After |
| 7/1/1922 | NO | Hollocher | Traded away | DBL | | After |
| 7/1/1922 | SC | Nehf | Traded away | DBL | | After |
| 7/1/1922 | Tex | Bancroft | Traded away | DBL | | After |
| 7/1/1922 | Tex | Bigbee | Traded away | DBL | | After |
| 7/1/1922 | Tex | Morton | Traded away | DBL | | After |
| 7/1/1922 | Tex | Schang | Traded away | DBL | | After |
| 7/1/1922 | Tex | Tierney | Traded away | DBL | | After |
| 7/4/1922 | Alt | Duncan | Acquired via trade | DBL | | After |
| 7/4/1922 | Alt | Leverett | Acquired via trade | DBL | | After |
| 7/4/1922 | Alt | Pfeffer | Acquired via trade | DBL | | After |
| 7/4/1922 | Alt | Stock | Acquired via trade | DBL | | After |
| 7/4/1922 | Bla | Collins,P | Acquired via trade | DBL | | After |
| 7/4/1922 | Bla | Ruth | Acquired via trade | DBL | | After |
| 7/4/1922 | KS | Decatur | Acquired via trade | DBL | | After |
| 7/4/1922 | KS | Faber | Acquired via trade | DBL | | After |
| 7/4/1922 | KS | Witt | Acquired via trade | DBL | | After |
| 7/4/1922 | Mac | Meusel,I | Acquired via trade | DBL | | After |
| 7/4/1922 | Mac | Sisler | Acquired via trade | DBL | | After |
| 7/4/1922 | Mid | Lee | Acquired via trade | DBL | | After |
| 7/4/1922 | Mid | McManus | Acquired via trade | DBL | | After |
| 7/4/1922 | NO | Hollocher | Acquired via trade | DBL | | After |
| 7/4/1922 | SC | Nehf | Acquired via trade | DBL | | After |
| 7/4/1922 | Tex | Bancroft | Acquired via trade | DBL | | After |
| 7/4/1922 | Tex | Bigbee | Acquired via trade | DBL | | After |
| 7/4/1922 | Tex | Morton | Acquired via trade | DBL | | After |
| 7/4/1922 | Tex | Schang | Acquired via trade | DBL | | After |
| 7/4/1922 | Tex | Tierney | Acquired via trade | DBL | | After |
| 7/7/1922 | Bla | Acosta | Demoted to reserve roster | | | Before |
| 7/7/1922 | Bla | Barber | Demoted to reserve roster | | | Before |
| 7/7/1922 | Bla | Bruggy | Promoted to active roster | | | Before |
| 7/7/1922 | Bla | Gaston | Promoted to active roster | | | Before |
| 7/7/1922 | Bla | Pinto | Demoted to reserve roster | | | Before |
| 7/7/1922 | Bla | Wheeler | Promoted to active roster | | | Before |
| 7/18/1922 | Mid | Fitzgerald | Acquired via trade | Tex | | After |
| 7/18/1922 | Mid | Russell,R | Traded away | Tex | | After |
| 7/18/1922 | Tex | Fitzgerald | Traded away | Mid | | After |
| 7/18/1922 | Tex | Russell,R | Acquired via trade | Mid | | After |
| 7/19/1922 | KS | Bailey | Demoted to reserve roster | | | Before |
| 7/19/1922 | KS | Baumgartner | Promoted to active roster | | | Before |
| 7/19/1922 | KS | Benton,R | Promoted to active roster | | | Before |
| 7/19/1922 | KS | Bottomley | Demoted to reserve roster | | | Before |
| 7/19/1922 | KS | O'Rourke | Placed on Injured List | | 7/12/1922 | Before |
| 7/19/1922 | KS | Yaryan | Promoted to active roster | | | Before |
| 7/19/1922 | Tex | Russell,R | Promoted to active roster | | | Before |
| 7/24/1922 | Bla | Connolly | Acquired via trade | Aus | | After |
| 7/24/1922 | Bla | Dodge | Acquired via trade | Aus | | After |
| 7/24/1922 | Bla | Fletcher | Traded away | Aus | | After |
| 7/24/1922 | Bla | Glazner | Traded away | Aus | | After |
| 7/24/1922 | Bla | Kimmick | Acquired via trade | Aus | | After |
| 7/24/1922 | Bla | Mann | Traded away | Aus | | After |
| 7/24/1922 | Bla | Martin | Acquired via trade | Aus | | After |
| 7/24/1922 | Bla | Strunk | Traded away | Aus | | After |
| 8/25/1922 | Tex | Mokan,J | Demoted to reserve roster | | | Before |
| 8/25/1922 | Tex | O'Neill,H | Promoted to active roster | | | Before |
| 8/31/1922 | KS | Bailey | Promoted to active roster | | | Before |
| 8/31/1922 | KS | Baumgartner | Demoted to reserve roster | | | Before |
| 9/6/1922 | SC | Austin | Promoted to active roster | | | Before |
| 9/6/1922 | SC | Baker | Placed on Injured List | | 9/3/1922 | Before |
| 9/6/1922 | SC | Hartnett | Promoted to active roster | | | Before |
| 9/6/1922 | SC | Milan | Promoted to active roster | | | Before |
| 9/30/1922 | Bla | Barber | Promoted to active roster | | | Before |
| 9/30/1922 | Bla | Freeman | Demoted to reserve roster | | | Before |
| 9/30/1922 | Bla | Gaston | Demoted to reserve roster | | | Before |
| 7/9/2025 | Bla | Fletcher | Acquired via trade | Aus | | After |
| 7/9/2025 | Bla | Mann | Acquired via trade | Aus | | After |
| 8/1/2025 | Tex | Ellerbe | Acquired via trade | BG | | After |
| 8/1/2025 | Tex | Lapan | Traded away | BG | | After |
| 8/9/2025 | Alt | Hooper | Acquired via trade | Aus | | After |
| 8/9/2025 | Alt | Wood | Traded away | Aus | | After |